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Connect Epic and Twilio — HIPAA-Compliant, No Code

Knack Health connects Epic to Twilio with automated workflows built for healthcare teams. Send HIPAA-compliant SMS reminders, appointment alerts, and patient notifications triggered by Epic events — no developers, signed BAA included.
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Epic and Twilio Integration
Trusted by hundreds of healthcare organizations. Signed BAA included.

What You Can Do When Epic Connects to Twilio

Epic holds your patient appointments and clinical data. Twilio powers your SMS and communications infrastructure. Knack Health automates the patient messaging between them — HIPAA-compliant, no code.

Appointment scheduled → SMS confirmation sent to patient automatically

When an appointment is created in Epic, Knack triggers a Twilio SMS to the patient confirming the date, time, and location — no manual outreach required.

24 hours before appointment → automated reminder SMS fired

Knack runs a scheduled workflow that checks Epic for upcoming appointments and fires a Twilio reminder SMS to each patient 24 hours in advance — reducing no-shows without staff effort.

Appointment no-show → re-engagement SMS triggered automatically

When an appointment is marked no-show in Epic, Knack triggers a Twilio message to the patient offering to reschedule — turning a missed visit into a re-booked one.

Post-visit → follow-up SMS with care instructions or survey link

When an appointment is completed in Epic, Knack fires a Twilio SMS to the patient with post-visit instructions, a care reminder, or a link to a satisfaction survey.
Epic and Twilio Integration

Set Up in Minutes. No Developers Required.

Build your healthcare app

Use Knack’s no-code builder — or AI — to create the app your team actually needs. Patient intake, care coordination, scheduling, billing — start from a template or build from scratch.

Connect with Flows

Add a Flow inside your Knack app to connect to Epic or Twilio. Choose your trigger, set your actions, and map your data fields. No code required.

Automate and run

Your workflow runs automatically from that point on. Every step is logged, HIPAA-compliant, and visible in your Flows dashboard.

What Healthcare Teams Automate with Knack Health

Epic and Twilio Integration - Appointment Reminders

Appointment Reminders: Reduce no-shows with automated SMS

Scheduled Flows check Epic daily and fire Twilio reminder messages to patients before each appointment — cutting no-show rates without adding work for your front desk.
Epic and Twilio Integration - Patient Communications

Patient Communications: Trigger the right message from every Epic event

Appointment confirmations, status changes, and visit completions in Epic automatically trigger the right Twilio message to the right patient at the right time.
Epic and Twilio Integration - Re-Book No Shows

Re-engagement: Turn no-shows into rebooked appointments

No-show flags in Epic trigger automated Twilio outreach — a friendly SMS that invites the patient to reschedule, with a link to your booking flow if available.
Epic and Twilio Integration - Post-Visit Engagement

Post-Visit: Keep patients engaged after every appointment

Completed visits in Epic trigger Twilio follow-up messages — care instructions, prescription reminders, survey links, or next appointment prompts — all automated, all logged.

HIPAA Compliance Built Into Every Connection

Every workflow you run through Knack Health is covered — encrypted, logged, and backed by a signed BAA.

Signed BAA

Included on every HIPAA plan. No negotiating, no waiting.

Encrypted Data

All data encrypted in transit and at rest on every plan.

Role-Based Access

Control exactly who can view, edit, or trigger each workflow.

Record Change Logs

Every action is logged with a timestamp and user ID. Always on.

SOC 2 Type II Certified

Independently verified security controls across the platform.

Ready to connect Epic and Twilio?

Start building for free — no credit card required. Or talk to our team about your specific workflow.
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HIPAA plans start at $625/month. Includes signed BAA, encrypted data, and record change logs.

Connect Epic with Twilio FAQs

Is this integration HIPAA-compliant?
Yes. All connections built through Knack Health run on our HIPAA-compliant infrastructure. Every HIPAA plan includes a signed Business Associate Agreement, encrypted data handling, and record change logs.
No. Knack Flows uses a visual, no-code builder. You connect [EHR] and [CONNECTOR] by selecting triggers and actions from a menu — no API keys, no code, no engineers required.
Most integrations are live in under an hour. Complex multi-step workflows may take a few hours depending on your data mapping requirements.
Twilio offers HIPAA-eligible services and signs BAAs with covered entities and business associates. When the workflow runs through Knack Health, all data is encrypted in transit and every message event is logged. We recommend keeping PHI in SMS messages to a minimum — appointment times and callback numbers are generally acceptable, while clinical details should be handled through more secure channels.
Yes. Knack Flows supports conditional logic — so a new patient appointment can trigger a different message than a follow-up visit, and a specialist appointment can include specialty-specific instructions. You define the message templates and the conditions that trigger each one.