The HIPAA-compliant backend built for Base44

Build your frontend in Base44. Connect Knack Health for HIPAA-compliant data storage, a signed BAA, and no-code infrastructure built for healthcare.

Architecture diagram showing a frontend built in Base44 connecting bidirectionally through a Knack MCP Server and a Runtime Data API to a Knack Health HIPAA-compliant backend.

You built something real. Now make it ready for real patients.

The moment your app touches real patient data, protected health information (PHI) needs to live somewhere that is encrypted, access-controlled, audit-logged, and covered by a signed Business Associate Agreement. Base44 doesn’t offer that, but Knack Health does — connect a Base44 frontend directly to our HIPAA-compliant infrastructure, and deploy your app with peace of mind. 

Keep your Base44 frontend

Your Base44 UI stays exactly as it is. Keep iterating in Base44's AI builder — nothing visible to users changes. The integration works at the data layer, not the interface layer.

PHI in compliant infrastructure

Patient data flows directly to Knack Health's HIPAA backend — encrypted at rest and in transit, hosted on AWS GovCloud and in supported U.S. regions, covered by a signed BAA. It never touches Base44's infrastructure.

No engineers required

Knack Health is a no-code platform. Manage your database, forms, workflows, and user roles through a visual interface — no SQL, no backend developers, no infrastructure decisions to make or maintain.

How Base44 and Knack Health work together

Build your data schema in Knack Health.

Before connecting, define your tables, fields, and relationships in Knack. This becomes the source of truth for how PHI is structured: patient records, appointments, clinical notes, whatever your app needs.

Connect Base44 to Knack via MCP

Base44's AI builder connects to your Knack schema through Knack's MCP server. Once connected, the AI understands your actual data structure and can generate forms and components that map to real Knack fields, not a generic placeholder structure.

Build your frontend against the Knack schema

Continue building in Base44 the way you always have. The AI builder now understands your actual data structure — generating accurate forms, tables, and UI components connected to real Knack fields.

PHI flows through Knack at runtime

When your app is live, all record operations run through Knack's runtime API: creating, reading, updating, and deleting patient data. PHI goes directly to Knack Health's compliant backend. Base44 handles the interface.

Sign your BAA and go live

Execute your BAA with Knack Health before any real PHI enters the system. Your app is live on HIPAA-compliant infrastructure with a signed agreement covering the data layer.

Check out our full guide here: Connecting Base44 to Knack

Screenshot composite showing the Knack backend interface with a Users table open alongside a Base44 chat prompt reading "Build a patient intake form using the Knack backend," illustrating the Knack to Base44 integration powered by the Knack MCP Server and Runtime Data API.

Watch the Tutorial: Connecting Knack and Base44

What about AWS, Azure, or Google Cloud?

The major cloud providers are the right choice if you have a DevOps team and six to twelve months to configure HIPAA-compliant infrastructure from scratch. For a team that built a prototype in Base44, that is the wrong trade. HIPAA on AWS means VPC configuration, encrypted RDS instances, CloudTrail audit logging, IAM policies, and an ongoing maintenance burden before a single patient record enters the system.

Knack Health gives you the same compliance outcome: hosting, encryption, audit logging, access controls, and a signed BAA. All of it is handled at the platform level, with no infrastructure work required.

What healthcare teams are building with this architecture

From intake to inventory, streamline every step of care.

Every clinic, network, and lab runs on its own mix of systems. Knack Health brings them together. Customize every field, form, and workflow to match how your team actually works.

Everything your healthcare app needs —
in one platform

HIPAA-compliant infrastructure

Secure hosting, encryption in transit and at rest, and locked-on security defaults that can't be accidentally disabled.

Signed BAA included

A Business Associate Agreement is included with every Knack Health HIPAA plan, executed before PHI enters the platform.

No-code DB

Build and manage tables, fields, and relationships visually. No SQL, no backend developers, no infrastructure decisions.

500+ HIPAA-compliant integrations

Connect to the tools your team uses via Knack Flows — a no-code automation layer built with HIPAA compliance in mind.

Unlimited apps, users, and builders

One flat monthly price. No per-project compute billing, per-seat charges, or billing surprises as you scale.

HIPAA-compliant AI workflows

Build AI-powered automations via Knack Flows using self-contained, HIPAA-compliant LLMs. PHI stays inside compliant infrastructure throughout.

Audit logging and access controls

Record change logs, role-based permissions, and page-level access controls built to support HIPAA audit requirements.

MCP server support

Base44's AI builder connects to your Knack schema via Knack's MCP server — so your frontend stays in sync with your data model as it evolves.

Featured Stories

Trusted by healthcare organizations worldwide.

From private clinics to national health systems, Knack Health helps teams modernize safely.

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Royal Free London NHS Foundation Trust

digitized reporting and reduced manual data entry by 70%.

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Social Health Research

built a HIPAA-compliant portal for sharing patient stories to improve therapies and care pathways.

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Arizona Autism

automated care-plan tracking and staff scheduling across multiple centers and administrators.

Already built something in Base44?

If you have an existing Base44 prototype with data in it, our team can help migrate your data models, records, and workflows into Knack Health — without rebuilding your frontend from scratch.

Talk to us about your Base44 app

Tell us what you’re building and where you are in the process. We’ll walk through the architecture, confirm the right setup for your use case, and get you started on a HIPAA plan.

FAQ

Does Knack Health replace Base44?

No. Knack Health is the backend — the data layer where PHI is stored and managed. Base44 remains your frontend development environment. Patient data flows through Knack Health’s HIPAA-compliant infrastructure instead of Base44’s default backend; nothing about your Base44 interface changes.

No. Because PHI flows directly between the user’s browser and Knack Health’s backend via Knack’s runtime API, Base44’s infrastructure never stores or processes patient data. The compliance boundary sits at the Knack layer — which is where the BAA applies.

Yes. A signed Business Associate Agreement is included with every Knack Health HIPAA plan. It must be executed before any PHI is stored in the platform.

Yes. Base44 stays your frontend development environment throughout. The MCP server connection keeps Base44’s AI builder in sync with your Knack schema as your data model evolves.

Most teams have the Base44 + Knack Health integration configured within a day. Building out your full data schema and frontend typically takes longer — timeline depends on your app’s complexity.

If your prototype has data in Base44 that needs to move, our team can help with migration. If you’re still in the build phase, you can start fresh with Knack Health as the backend from day one.